- Trade - San Francisco trades 2013 6th round selections, San Francisco's (87th overall) and San Diego's (91st overall) to Chicago in return for a 2013 5th round selection (67th overall).
- Trade - San Francisco trades a 2013 5th round selection (72nd overall) and a 2014 2nd round selection to Mississauga in return for Denver's 2013 3rd round selection (33rd overall).
- Trade - Dallas trades a 2014 3rd round selection to Miami in return for a 2013 3rd round selection (47th overall).
- Trade - Arizona trades 2013 selections, 1st round (12th overall), Washington's 2nd round (19th overall), and a 6th round (92nd overall) to San Diego in return for a 2013 1st round selection (2nd overall).
- Trade - Buffalo trades DL GERALD McCOY to San Francisco in return for RB DANNY WOODHEAD and WR ANQUAN BOLDIN.
- Trade - Denver trades a 2013 2nd round selection (17th overall), a 2014 2nd round selection and a 2015 4th round selection to Mississauga in return for a 2013 1st round selection (5th overall).
- Trade - Denver trades DL OSI UMENYIORA to San Diego in return for a 2015 3rd round selection. Denver also agrees to cover $1,000,000 or O. Umenyiora's salary.
- San Francisco released RB CEDRIC BENSON, LBs LARRY ENGLISH & BRADIE JAMES, and DL RICHARD SEYMOUR.
- LEAGUE - Club Activity Freeze lifted.